First, we will simplify the expression step by step:

Step 1: Calculate within the parenthesis first:

5,05:1 = 5,05
40 - 2 = 38
8 * 5 = 40
40/6 = 6.67

(5.05 + 38 6.67) 3 + (-16)*(0.1875)

Step 2: Simplify the expression within the parenthesis:

(5.05 + 253.46) 3 + (-16)(0.1875)

Step 3: Add the numbers within the parenthesis:

(258.51) 3 + (-16)(0.1875)

Step 4: Multiply 258.51 by 3:

775.53 + (-16)*(0.1875)

Step 5: Multiply -16 by 0.1875:

775.53 - 3

Step 6: Finally, subtract:

772.53

Therefore, the final result is 772.53.