First, evaluate the expression at the given values of x and y:
-8(-4)(10) + 4(10) - 4(-4) - 3(10) + 2(-4) + 8(-4)(10)= 320 + 40 + 16 - 30 - 8 - 320= 18
Therefore, the value of the expression -8xу + 4у - 4x - 3у + 2x + 8ху when x=-4 and y=10 is 18.
First, evaluate the expression at the given values of x and y:
-8(-4)(10) + 4(10) - 4(-4) - 3(10) + 2(-4) + 8(-4)(10)
= 320 + 40 + 16 - 30 - 8 - 320
= 18
Therefore, the value of the expression -8xу + 4у - 4x - 3у + 2x + 8ху when x=-4 and y=10 is 18.