To simplify this expression, we need to follow the order of operations (PEMDAS/BODMAS):

First, perform any operations inside parentheses:
5107-107*6+35 = 5107 - 642 + 35 = 4466

Next, perform any multiplication and division from left to right:
4*x + 180 = 4x + 180

Calculate the final expression:
(4x + 180) / 3.25 = (4x + 180) / 3.25 = 4x / 3.25 + 180 / 3.25
= 1.23x + 55.38

Therefore, the simplified expression is 1.23x + 55.38.