(52×390-12863)×(12380÷40-207)=
(20280-12863)×(309.5-207)= 7427 × 102.5= 761027.5
(59531-58926)×6004-1221485=
605 × 6004 - 1221485= 3633020 - 1221485= 2411535
Therefore, the final answer is 761027.5 and 2411535.
(52×390-12863)×(12380÷40-207)=
(20280-12863)×(309.5-207)
= 7427 × 102.5
= 761027.5
(59531-58926)×6004-1221485=
605 × 6004 - 1221485
= 3633020 - 1221485
= 2411535
Therefore, the final answer is 761027.5 and 2411535.